Sickling and Malaria

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The relationship of serum gamma-globulin concentration to malaria and sickling.

The serum protein patterns of groups of Nigerians including 98 children partially protected by "daraprim" against malaria, and 113 unprotected children, have been studied. The protected children have a significantly lower concentration of serum gamma globulin than the unprotected children from the age of 12 months onwards. In children, sicklers have a significantly higher serum gamma globulin t...

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Sickle cell trait (SCT) occurs in about 8% of African-Americans and is often described to be of little clinical consequence. Over time, a number of risks have emerged, and among these are rare but catastrophic episodes of sudden death in athletes and other individuals associated with physical activities which is often described as exercise collapse associated with sickle trait (ECAST). Despite ...

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Macular and perimacular vascular remodelling sickling haemoglobinopathies.

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Erythrocyte sickling during exercise and thermal stress.

OBJECTIVE To examine effects of exercise in the heat and fluid intake on erythrocyte sickling and neutrophil activation in carriers of sickle cell trait (HbAS). DESIGN, SETTING, AND PARTICIPANTS Six African American men (2 HbAS; 42% HbS, 4 HbAA; 20.7 +/- 0.8 years; 87.4 +/- 9.6 kg) participated in 2 randomized sessions (separate days) each consisting of 45 minutes of brisk walking (treadmill)...

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ژورنال

عنوان ژورنال: BMJ

سال: 1954

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.4897.1162